EhPKMT2-interacting proteins

Hypothesis. The protein lysine methyltransferase 2 (EhPKMT2) regulates several cellular/molecular essencial processes of Entamoeba histolytica. Tse proteins were identified by pulldown assays usin the recombinant EhPKMT2 as bait. The results indicate that this PKMT is involved in transcription regulation, translation, metabolism, stress response and cytoskeleton dynamics, suggesting that this protein coul be an atractive target to develop new therapeutic strategies against amebiasis