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Crystal structure of spleen tyrosine kinase complexed with r9021

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Protein Data Bank Japan2023-09-13 更新2026-03-21 收录
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Crystal structure of spleen tyrosine kinase complexed with r9021 Descriptor: 6-{[(1R,2S)-2-aminocyclohexyl]amino}-4-[(5,6-dimethylpyridin-2-yl)amino]pyridazine-3-carboxamide, Tyrosine-protein kinase SYK Authors: Lukacs, C, Slade, M. Deposit date: 2012-08-03 Release date: 2013-08-14 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.35 Å) Cite: A specific SYK inhibitor blocks B Cell Receptor, Fc Receptor, and Toll-like Receptor 9 pathways for the treatment of inflammatory diseases. To be Published

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2012-08-03
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