NA, not assessed. *Significant after Bonferoni Multiple testing. aSignificant excess of missense and rare missense variants versus silent variants, compared to the rest of genes pooled together in eac
It is plausible that variants in the ACE2 and TMPRSS2 genes might contribute to variation in COVID-19 severity and that these could explain why some people become very unwell whereas most do not. Exom
The shared VCF file contains the final set of protein‑altering variants retained in COBT study after our complete filtering and annotation pipeline, which included restriction to high‑confidence codin
