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Characterisation of the effects of in situ fixation on DNA methylation levels

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干细胞与再生医学数据中心2022-02-20 更新2024-03-06 收录
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Focusing on adult skeletal muscle stem cells, we have developed a protocol that circumvents the impact of the isolation procedures and captures the cells in their native quiescent state. We show that current isolation protocols induce major transcriptional changes accompanied by specific histone modifications, while having negligible effects on DNA methylation.
提供机构:
Institut Pasteur
创建时间:
2022-02-20
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