Heliaquanoids A–E, Five Sesquiterpenoid Dimers from Inula helianthus-aquatica
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https://figshare.com/articles/dataset/Heliaquanoids_A_E_Five_Sesquiterpenoid_Dimers_from_Inula_helianthus-aquatica/7902224
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资源简介：
Heliaquanoid
A (1), the first exo-2,4-linked Diels–Alder
adduct between a pseudoguaianolide
dienophile and a guaianolide diene, and heliaquanoids B–E (2–5), four new 2,4-linked Diels–Alder
adducts between a xanthanolide dienophile and a guaianolide diene,
were isolated from stems and leaves of Inula helianthus-aquatica. Their structures were determined by NMR spectroscopy, a modified
Mosher’s method, electronic circular dichroism, and X-ray diffraction
analysis. Compounds 2 and 3 exhibited moderate
cytotoxic activities against HL-60 cells with IC50 values
of 7.5 and 4.9 μM, respectively.
创建时间：
2019-03-27
