A model of molecular characteristics to classify WHO Grade III glioma patients. A model of molecular characteristics to classify WHO Grade III glioma patients

Combing WHO classification and molecular characteristics to analysis gliomas more and more important. But Grade III glioma samples have a big difference within the group had not been reported as far as we know. In this study, we proposed a model to evaluate diagnosis and prognosis of Grade III glioma patients, and two independent datasets indicated that the model has a good predictive ability. Therefore, this strategy provides a new method to assist diagnosis and treatment of Grade III glioma patients. Overall design: There are 225 samples. Gene expression profiling analysis of these samples was performed using Agilent 4x44K human whole genome gene expression microarray.