Characterizing Neonatal Heart Maturation, Regeneration, and Scar Resolution Using Spatial Transcriptomics [spatial]

We use spatial transcriptomics to establish regional transcriptional profile of neonatal heart tissue obtained at indicated timpoints after apical resection surgery. Overall design: The cardiac apex was resected at P2, within the regenerative window, and hearts were isolated at indicated timepoints for spatial transcriptomics.