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Expression data from pancreatic beta cells isolated from differentially weaned mice.. Mus musculus

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NIAID Data Ecosystem2026-03-09 收录
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA271217
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Transcriptome analysis reveals that in pancreatic beta cells weaning increases the expression of genes involved in replication licensing, suggesting a mechanism to increased responsiveness to the mitogenic activity of high glucose. Overall design: β cells were sorted from dissociated islets of P25 insulin-Cre; Rosa26-LSL-YFP mice (Gannon et al., 2000; Srinivas et al., 2001) that were either suckling or prematurely weaned at P18. YFP+ FACS-sorted cells were subjected for RNA extraction and hybridization on Affymetrix microarrays
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2014-12-26
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