Crystal Structure of Human p38alpha complexed with SD-0006

Crystal Structure of Human p38alpha complexed with SD-0006 Descriptor: 2-fluoro-4-[4-(4-fluorophenyl)-1H-pyrazol-3-yl]pyridine, 2-{4-[5-(4-chlorophenyl)-4-pyrimidin-4-yl-1H-pyrazol-3-yl]piperidin-1-yl}-2-oxoethanol, Mitogen-activated protein kinase 14 Authors: Shieh, H.-S, Kurumbail, R.G, Stegeman, R.A, Williams, J.M. Deposit date: 2009-05-26 Release date: 2009-07-14 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.88 Å) Cite: Structural bioinformatics-based prediction of exceptional selectivity of p38 MAP kinase inhibitor PH-797804. Biochemistry, 48, 2009