BIOGRID CURATED DATA FOR LRS4 (Saccharomyces cerevisiae (S288c))

Protein-Protein, Genetic, and Chemical Interactions for LRS4 (Saccharomyces cerevisiae (S288c)) curated by BioGRID (https://thebiogrid.org); DEFINITION: Nucleolar protein that forms a complex with Csm1p; and then Mam1p at kinetochores during meiosis I to mediate accurate homolog segregation; required for condensin recruitment to the replication fork barrier site and rDNA repeat segregation

蛋白质-蛋白质、遗传学及化学相互作用数据集，针对酵母菌（酿酒酵母S288c）中的LRS4（核仁蛋白）由BioGRID（https://thebiogrid.org）整理；定义：一种与Csm1p形成复合物的核仁蛋白；并在减数第一次分裂中与Mam1p在着丝粒结合，以介导同源染色体精确分离；对于凝聚素在复制叉屏障位点招募及rDNA重复序列分离至关重要。