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Efficient and Regioselective Synthesis of Novel Functionalized Dispiropyrrolidines and Their Cytotoxic Activities

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NIAID Data Ecosystem2026-03-08 收录
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https://figshare.com/articles/dataset/Efficient_and_Regioselective_Synthesis_of_Novel_Functionalized_Dispiropyrrolidines_and_Their_Cytotoxic_Activities/2316430
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资源简介:
An efficient and regioselective synthesis of novel functionalized dispiropyrrolizidine derivatives via a three-component [3 + 2] cycloaddition reaction of azomethine ylides is described. This protocol has the advantages of high efficiency, mild reaction conditions, a one-pot procedure, and convenient operation. Many of these compounds were evaluated for their antiproliferative properties in vitro against cancer cells and several compounds were found to have good activities.
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2014-03-10
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