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Mastoiditis caused by novel sequence type of non toxigenic toxin gene-bearing (NTTB) Corynebacterium diphtheriae

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NIAID Data Ecosystem2026-05-02 收录
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A patient presented with mastoiditis and Corynebacterium diphtheriae was isolated. The strain was positive by PCR for toxin, but negative with a toxin Elek test. Whole genome sequencing revealed that the toxin gene was disrupted by the insertion sequence, IS1132. This result explains the Elek test.

创建时间:
2025-08-02
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