Gastric Cancer (GC) is a highly heterogeneous disease. To identify potential clinically actionable therapeutic targets that may inform individualized treatment strategies, we performed whole-exome seq
Somatic genome rearrangements and recurrent fusion genes are thought to play important roles in cancer development. We applied the long span DNA-PET approach to comprehensively characterize the SVs of
BackgroundTP53 gene mutation is one of the most common mutations in human bladder cancer (BC) and has been implicated in the progression and prognosis of BC. MethodsRNA sequencing data and TP53 mutati
The presence of diffuse anaplasia in Wilms tumours (DAWT) is associated with TP53 mutations and poor outcome. As patients receive intensified treatment, we sought to identify whether TP53 mutational s
