Supplementary Material for Lee and George, et al. Association between lifetime smoking and cutaneous squamous cell carcinoma: A 2-sample Mendelian randomization study. JAAD International

Supplementary Material for Lee and George, et al. Association between lifetime smoking and cutaneous squamous cell carcinoma: A 2-sample Mendelian randomization study. JAAD International. Supplementary Figure 1. Association of cigarette smoking initiation-associated variants with the risk of cSCC. Supplementary Figure 2. Association of cigarettes per day-associated variants with the risk of cSCC. Supplementary Table 1. Description of the samples used for exposures and outcome. Supplementary Table 2. List of the cohorts used for cigarette smoking initiation and cigarettes per day exposures. Supplementary Table 3. Genetic instruments (N=236) for cigarette smoking initiation. Supplementary Table 4. Genetic instruments (N=45) for cigarettes per day. Supplementary Table 5. Genetic instruments (N=121) for lifetime smoking. Supplementary Table 6. Mendelian randomization leave-one-out analysis for cigarette smoking initiation showing a lack of association with cSCC. Supplementary Table 7. Mendelian randomization leave-one-out analysis for cigarettes per day showing a lack of association with cSCC. Supplementary Table 8. Mendelian randomization leave-one-out analysis for lifetime smoking suggesting evidence of causality with cSCC. Supplementary Table 9. Horizontal pleiotropy and heterogeneity values.