Crystal structure of TYK2 kinase domain in complex with compound 25
收藏Protein Data Bank Japan2024-11-06 更新2026-04-19 收录
下载链接：
https://pdbj.org/mine/summary/7uyt
下载链接
链接失效反馈官方服务：
资源简介：
Crystal structure of TYK2 kinase domain in complex with compound 25 Descriptor: 6-{[(2M)-2-(2-chloro-6-fluorophenyl)-5-oxo-5H-pyrrolo[3,4-b]pyridin-4-yl]amino}-N-ethylpyridine-3-carboxamide, Non-receptor tyrosine-protein kinase TYK2 Authors: Toms, A.V, Leit, S, Greenwood, J.R, Mondal, S, Carriero, S, Dahlgren, M, Harriman, G.C, Kennedy-Smith, J.J, Kapeller, R, Lawson, J.P, Romero, D.L, Shelley, M, Wester, R.T, Westlin, W, Mc Elwee, J.J, Miao, W, Edmondson, S.D, Massee, C.E. Deposit date: 2022-05-07 Release date: 2022-08-24 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (2.14 Å) Cite: Potent and selective TYK2-JH1 inhibitors highly efficacious in rodent model of psoriasis. Bioorg.Med.Chem.Lett., 73, 2022
创建时间：
2022-05-07
