Further Wnt/β-catenin signaling inhibition sensitizes hypoxic OS cells to doxorubicin.
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MG-63 OS cells were treated with increasing concentrations of doxorubicin under hypoxic conditions in the presence of the tankyrase inhibitor XAV939, the porcupine inhibitor IWP-2, or DMSO alone. Half maximal inhibitory concentrations (IC50) were calculated, and the percent IC50 relative to DMSO alone was determined. Asterisks indicate statistical significance (*p
创建时间：
2016-02-23
