We provide comprehensive datasets of aging-related genes, pathways and ligand-receptor interactions in nearly all brain cell types. hese data reveal that aging, rather than inducing a universal progra
The cellular form of the prion protein (PrPC) is a normal constituent of neuronal cell membranes. The protein misfolding causes rare neurodegenerative disorders known as transmissible spongiform encep
The goal of this study is to define the epigenetic and transcriptional changes that occur across brain regions and cell types during aging. We profiled chromatin accessibility using single-nucleus ATA
