Serological mechanisms driving cardiotoxicity in COVID-19

The aim of the study is to investigate the effects of serum from COVID-19 patients on pluripotent stem cells derived cardiomyocytes (PSC-CMs) Overall design: To investigate the effects of serum, PSC-CMs were treated for 4 days in the presence of serum coming from control, mild or severe COVID-19 patients. To investigate COVID-19 specific pathways, PSC-CMs were also treated with plasma coming from ARDS patients