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Role of CCL7 regulates the immunosuppressive activity of TAMs

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NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP562185
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Ccl7 myeloid cell deficient mice showed a decreased accumulation of immunosuppressive tumor-associated macrophages and increased infiltration of activated CD8+ T cells in the tumor microenvironment. To determine the role of Ccl7 involving in the immunosuppressive activity of tumor-associated macrophages. Total RNA was isolated from sorted tumor-associated macrophages from MC38 tumor-bearing control or Ccl7 myeloid cell KO mice.
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2025-06-01
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