five

RNAseq of mouse mammary luminal cells

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https://www.ncbi.nlm.nih.gov/sra/SRP256316
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The mammary epithelia are mainly composed of two distinct lineages, the basal and luminal cells. In our MMTV-Cre; Brca1flox/flox mouse model, we found the Brca1 knockout mainly occurred in the luminal cells, which will lead the mammary tumorigenesis. To investigate the Brca1 deficiency mediated mammary tumorigenesis, we sorted the luminal cells from wild type mice and MMTV-Cre; Brca1flox/flox mice for RNAseq analysis. Overall design: 5 mouse luminal cells samples were collected for RNA sequencing.
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2021-12-10
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