Contribution of Age, Brain Region, Mood Disorder Pathology, and Interindividual Factors on the Methylome of Human Microglia
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE191200
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资源简介：
Total of 56 microglia samples from postmortem brain tissue of four different brain regions, medial frontal gyrus (MFG), superior temporal gyrus (STG), subventricular zone (SVZ) and thalamus (THA), of 22 donors, encompassing 1 patient with schizophrenia, 13 patients with mood disorder pathology, and 8 control subjects, were isolated and assayed using a genome-wide methylation array to characterize the DNA methylation landscape of human microglia and the factors that contribute to variations in the microglia methylome Genomic DNA from 59 subjects (28 with only pre-blast exposure sample, 31 with both pre- and post- blast exposure samples) was bisulfite converted and CpG methylation determined using Illumina Infinium MethylationEPIC BeadChip microarrays
创建时间：
2022-02-02
