NSCR_ Dataset_2023

The University of Turin (UniTo) released the second open-access dataset NSCR_Dataset collected for the NEUROSTEMCELLREPAIR (602278) and NSC-Reconstruct (874758) European stem cell consortia for neural cell replacement, reprogramming and functional brain repair (602278)  (https://www.nsc-reconstruct.com/en/index.do).

The NSCR_Dataset is a dataset of analysis of histological ex-vivo brain samples and behavioral parameters from Huntington's Disease (HD) rat models, after cell replacement approach of striatal progenitor cells in the lesioned striatum, at different time points. For for short time-points, see for details: https://www.sciencedirect.com/science/article/pii/S2213671120301089?via%3Dihub#app2); for long time points, see for details: https://stemcellres.biomedcentral.com/articles/10.1186/s13287-023-03422-4.

The UniTO team released this second dataset publicly. The dataset includes data obtained from HD rat models, divided into experimental groups and used in different histological and behavioral analysis. 

The dataset contains data from images of brain tissue stained for different cellular and molecular markers, acquired with transmission and confocal microscopes, from which analysis were performed, and the behavioral data obtained every month by testing the HD animals in different motor tasks.