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Genome-wide analysis of genome-editing specificity in human iPSCs by the CRISPR/Cas9 gene targeting system

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DataCite Commons2020-10-10 更新2025-04-09 收录
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Precise genome editing is crucial for realizing the full potential of human induced pluripotent stem cells (hiPSCs). Using six hiPSC lines including those with point mutations, we evaluated Cas9-mediated gene targeting with guide RNAs (gRNAs) targeting three disease-linked mutations and the AAVS1 locus.

提供机构:
CNGB
创建时间:
2018-10-20
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