Structure of human MTHFD2L in complex with TH7299

Structure of human MTHFD2L in complex with TH7299 Descriptor: (2S)-2-[[4-[[2,4-bis(azanyl)-6-oxidanylidene-1H-pyrimidin-5-yl]carbamoylamino]phenyl]carbonylamino]pentanedioic acid, 2'-MONOPHOSPHOADENOSINE-5'-DIPHOSPHATE, Probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 Authors: Gustafsson, R, Scaletti, E.R, Stenmark, P. Deposit date: 2021-12-03 Release date: 2022-10-12 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (2.1 Å) Cite: The First Structure of Human MTHFD2L and Its Implications for the Development of Isoform-Selective Inhibitors. Chemmedchem, 17, 2022