Mean percent sequence divergence between successfully enriched targets and reference sequence used to develop enrichment probes.

Target exon sequences were based on the Xenopus tropicalis reference genome. Species were not enriched for all exons. To estimate whether more conserved exons were more likely to be enriched, distance calculations between X. tropicalis and X. laevis were made for each target exon enriched for a given species and for each target exon that failed to enrich for that species. Standard errors are given in parentheses.