BRD4 bromodomain 1 in complex with HYB157
收藏Protein Data Bank Japan2023-10-11 更新2026-03-21 收录
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https://pdbj.org/mine/summary/6dl2
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BRD4 bromodomain 1 in complex with HYB157 Descriptor: 1,2-ETHANEDIOL, 3-benzyl-2,9-dimethyl-4H,6H-thieno[2,3-e][1,2,4]triazolo[3,4-c][1,4]oxazepine, Bromodomain-containing protein 4 Authors: Meagher, J.L, Stuckey, J.A. Deposit date: 2018-05-31 Release date: 2019-04-17 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.47 Å) Cite: Discovery of QCA570 as an Exceptionally Potent and Efficacious Proteolysis Targeting Chimera (PROTAC) Degrader of the Bromodomain and Extra-Terminal (BET) Proteins Capable of Inducing Complete and Durable Tumor Regression. J. Med. Chem., 61, 2018
创建时间：
2018-05-31
