KHK Bound to Compound 18
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KHK Bound to Compound 18 Descriptor: (2S,3R)-1-{4-[4-(3-aminooxetan-3-yl)phenyl]-7,7-difluoro-6,7-dihydro-5H-cyclopenta[d]pyrimidin-2-yl}-2-methylazetidin-3-ol, Ketohexokinase, SULFATE ION Authors: Ferrao, R.D. Deposit date: 2025-11-04 Release date: 2026-01-07 Last modified: 2026-01-14 Method: X-RAY DIFFRACTION (2.11 Å) Cite: The Discovery of GS-1291269: A Neutral Ketohexokinase (KHK) Inhibitor with an Unusual Thietane Amine Functional Group. J.Med.Chem., 69, 2026
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2025-11-04



