The histone-like protein AlgP regulon is distinct in nonmucoid and mucoid Pseudomonas aeruginosa and does not include alginate biosynthesis genes

Here we show that deletion of AlgP in mucoid P. aeruginosa strain does not result in nonmucoid phenotype or reduced alginate production. We also show that there is no significant overlap in the AlgP regulon between mucoid and nonmucoid P. aeruginosa strains. Overall design: The transcriptome of AlgP+/-mucoid and AlgP+/- nonmucoid P. aeruginosa was analyzed using RNA-seq with two biological replicates each.