Gene expression profile of bone marrow cells from Ogfrl1 deficient mouse at single cell level

Human data demonstrates loss of function mutations of OGFRL1 are a cause of autosomal recessive forms of cherubism. However, the gene function of OGFRL1 is unknown. We performed scRNAseq to investigate the gene function in bone marrow cells. Bone marrow cells were isolated from Ogfrl1 deficient and lettermate control mice.