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myeloid derived suppressor cells (MDSCs) from the spleen of melanoma bearing Atg5fl/fl and LYSMCre/Atg5fl/fl mice

NIAID Data Ecosystem2026-03-10 收录

骨髓来源抑制细胞

黑色素瘤免疫微环境

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA395259 数据链接链接失效反馈

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myeloid derived suppressor cells (MDSCs) fromthe spleen of melanoma bearing Atg5fl/fl and LYSMCre/Atg5fl/fl mice

应用场景：

创建时间：

2017-07-20

黑色素瘤免疫微环境

Treg细胞基因表达

Gene expression signature of Treg cells in B16 melanoma was measured and compared to B16-infiltrating CD4+ Tconv cells and CD8+ T cells as well as splenic Treg cells, CD4+ Tconv cells and CD8+ T cells

NIAID Data Ecosystem90

Mouse melanoma types with various genotypes

黑色素瘤免疫微环境

免疫逃逸机制

Only a subset of melanoma patients has evidence for spontaneous T cell infiltration into tumor sites, previously associated with clinical responses. However, the molecular mechanisms explaining absenc

NIAID Data Ecosystem70

Integrin β1 activation induces an anti-melanoma host response

黑色素瘤免疫微环境

整合素-TGFβ抗肿瘤机制

TGF-β is a cytokine thought to function as a tumor promoter in advanced malignancies. In this setting, TGF-β increases cancer cell proliferation, survival, and migration, and orchestrates complex, pro

Figshare2017-04-28 更新30

Functionally and Metabolically Divergent Melanoma-Associated Macrophages Originate from Common Bone-Marrow Precursors

肿瘤相关巨噬细胞

黑色素瘤免疫微环境

Melanomas display high numbers of tumor-associated macrophages (TAMs), which correlate with worse prognosis but also retain the potential to restore anti-tumor activity. Harnessing macrophages for the

NIAID Data Ecosystem70

Table_2_A Multi-Omics Analysis of Metastatic Melanoma Identifies a Germinal Center-Like Tumor Microenvironment in HLA-DR-Positive Tumor Areas.xlsx

黑色素瘤免疫微环境

免疫治疗生物标志物

The emergence of immune checkpoint inhibitors has dramatically changed the therapeutic landscape for patients with advanced melanoma. However, relatively low response rates and a high incidence of sev

NIAID Data Ecosystem50

myeloid derived suppressor cells (MDSCs) from the spleen of melanoma bearing Atg5fl/fl and LYSMCre/Atg5fl/fl mice

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