<b>Targeting CDK12 disrupts estrogen-receptor chromatin recruitment and ER-MED1 transcription in advanced ER+ breast cancer</b> (<i>ChIP-seq: siCDK12 binding peaks as detected using MACS2 in narrowPeak mode</i>)

We carried out ChIP-seq profiling of LY2 cells transfected with siRNA targeting CDK12 (siCDK12) and non-targeting control (siCtrl) for 48 hours followed by treatment with β-estradiol. Raw ChIPseq data files associated with this project are made available through GEO at: https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE309899