Protein Data Bank in Europe - Knowledge Base

PDBe-KB (Protein Data Bank in Europe - Knowledge Base) is a community-driven resource managed by the PDBe team, collating functional annotations and predictions for structure data in the PDB archive. PDBe-KB is a collaborative effort between PDBe and a diverse group of bioinformatics resources and research teams. The goal of PDBe-KB is two-fold: (i) to increase the visibility and reduce the fragmentation of annotations contributed by specialist data resources, and to make these data more findable, accessible, interoperable and reusable (FAIR) and (ii) to place macromolecular structure data in their biological context, thus facilitating their use by the broader scientific community in fundamental and applied research.

PDBe-KB（欧洲蛋白质数据库知识库，Protein Data Bank in Europe - Knowledge Base）是由PDBe团队管理的社区共建型资源，致力于整合蛋白质数据库（Protein Data Bank，PDB）档案中的结构数据功能注释与预测结果。PDBe-KB是PDBe与多类生物信息学资源及研究团队协同推进的合作项目。PDBe-KB的核心目标分为两点：其一，提升专业数据资源所贡献注释的可见性，减少其碎片化问题，同时使此类数据更符合可发现、可访问、可互操作与可复用（FAIR）原则；其二，将大分子结构数据置于对应的生物学语境中，以此助力更广泛的科研群体将其应用于基础研究与应用研究。

搜集汇总

背景与挑战

背景概述

PDBe-KB（Protein Data Bank in Europe - Knowledge Base）是一个由PDBe团队主导的开放协作联盟，致力于整合和丰富3D结构数据及其功能注释，以促进基础和应用研究。它通过汇集来自多个生物信息学资源的注释，提高数据的可发现性和可访问性，并将大分子结构置于生物学上下文中，服务于更广泛的科学社区。