Methylation of GMP-cap by RNA Methyltransferase
收藏reactome.org2025-01-09 收录
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In the final step of the capping reaction, the methyltransferase takes a methyl group from S-adenosyl-methionine to the N7 position of the cap guanine. N7G-methyltransferase (MT) mediated reaction can be represented as:<BR>GpppN(pN)n + S-adenosylmethionine (Adomet) ->m7GpppN(pN)n + S-adenosylhomocysteine (Adohcy).<P>
在加帽反应的最后一步，甲基转移酶从S-腺苷蛋氨酸中提取一个甲基基团并将其转移到帽子鸟嘌呤的N7位置。N7G甲基转移酶（MT）介导的反应可以表示为：<BR>GpppN(pN)n + S-腺苷蛋氨酸（Adomet）-> m7GpppN(pN)n + S-腺苷高半胱氨酸（Adohcy）。
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