Mutations rates of <i>pms1</i> metal coordination mutants on a low-copy plasmid in polymerase mutant strains <i>pol2M644G</i> and <i>pol3L612M</i>.

*Median rates of hom3-10 (Thr+) and lys2-10A (Lys+) reversion and inactivation of CAN1 (CanR) with 95% confidence interval (CI) in square brackets and fold increase relative to complementation with pRS316-PMS1 in parentheses. †p-value>0.05 for a difference in mutation rate of the pol2M644G mutant compared to the pol3L612M mutant when both mutants contained the same indicated pms1 mutant plasmid (Mann-Whitney test). ‡p-value<0.05 for a difference in mutation rate of the pol2M644G mutant compared to the pol3L612M mutant when both mutants contained the same indicated pms1 mutant plasmid (Mann-Whitney test).