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Marilyn G. Farquhar (2011) CIL:37180, Rattus, kidney cell, glomerular capillary endothelial cell, podocyte. CIL. Dataset

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Transmission electron micrograph of rat kidney filtration barrier. Micrograph illustrates the basement membrane between fenestrated capillary endothelium and podocyte foot processes at intermediate magnification. The series of images in this group have particular historic and cell biologic importance for determining the role of the glomerular basement membrane in urinary filtration, especially the charge properties and size selectivity in retention of proteins in the circulation. The images here clearly show the glomerular filtration barrier. The study also elucidated the role of the basement membrane in some forms of nephrosis. Image made available by James D. Jamieson and the Department of Cell Biology, Yale University School of Medicine.

大鼠肾脏滤过屏障的透射电子显微镜图像。微镜图像展示了在中等放大倍数下,有孔毛细血管内皮与足突之间的基膜结构。该组图像在历史上和细胞生物学上具有重要意义,对于确定肾小球基膜在尿液滤过中的作用,尤其是其在循环中对蛋白质保留的电荷特性和尺寸选择性具有重要意义。图像清晰展示了肾小球滤过屏障。研究还阐明了基膜在某些形式肾病中的作用。图像由詹姆斯·D·贾米森和耶鲁大学医学院细胞生物学系提供。
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