Interconversion of Human Lysosomal Enzyme Specificities Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-galactosidase A, GLYCEROL, ... Authors: Tomasic, I.B, Metcalf, M.C, Guce, A.I, Clark

Protein Data Bank Japan2024-11-27 更新40

Use of mice defective in interferon signaling to distinguish between primary and secondary pathological pathways in a mouse model of neuronal forms of Gaucher disease. Use of mice defective in interferon signaling to distinguish between primary and secondary pathological pathways in a mouse model of neuronal forms of Gaucher disease

神经退行性机制

溶酶体贮积症

The type 1 interferon (IFN) response is part of the innate immune response and best known for its role in viral and bacterial infection. However, this pathway is also induced in sterile inflammation s

NIAID Data Ecosystem10

A lysosome-plasma membrane-sphingolipid axis linking lysosomal storage to cell growth arrest

溶酶体贮积症

细胞信号通路

We used human fibroblasts loaded with sucrose as a simple model of lysosomal accumulation, and we verified by high-throughput RNA sequencing which processes were altered by the treatment at two differ

NIAID Data Ecosystem50

Trehalose reduces retinal degeneration, neuroinflammation and storage burden caused by a lysosomal hydrolase deficiency

溶酶体贮积症

自噬诱导疗法

The accumulation of undegraded molecular material leads to progressive neurodegeneration in a number of lysosomal storage disorders (LSDs) that are caused by functional deficiencies of lysosomal hydro

Figshare2018-06-19 更新20

Intra-assay variability of HuH-7 cells transduction measured by SGSH activity.

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