five

Pard3

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rgd.mcw.edu2025-03-22 收录
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https://rgd.mcw.edu/rgdweb/report/gene/main.html?id=620374
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ENCODES a protein that exhibits identical protein binding; phosphatidylinositol-3,4,5-trisphosphate binding; phosphatidylinositol-3-phosphate binding; INVOLVED IN bicellular tight junction assembly; establishment of epithelial cell polarity; protein targeting to membrane; PARTICIPATES IN protein kinase C (PKC) signaling pathway; chemokine mediated signaling pathway; endocytosis pathway; ASSOCIATED WITH autism spectrum disorder (ortholog); neural tube defect (ortholog); primary ovarian insufficiency (ortholog); FOUND IN axonal growth cone; cell-cell junction; neuronal cell body; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine

编码一种表现出相同蛋白质结合特性的蛋白质;磷脂酰肌醇-3,4,5-三磷酸结合;磷脂酰肌醇-3-磷酸结合;参与双细胞紧密连接的组装;上皮细胞极性的建立;蛋白质向膜靶向;参与蛋白激酶C(PKC)信号通路;趋化因子介导的信号通路;内吞作用通路;与自闭症谱系障碍(同源物)相关;神经管缺陷(同源物);原发性卵巢功能不全(同源物)相关;存在于轴突生长锥;细胞间连接;神经元细胞体;与17α-乙炔雌二醇;17β-雌二醇;2,3,7,8-四氯二苯并-对-二恶英相互作用。
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