Solvent-Controlled Asymmetric Strecker Reaction: Stereoselective Synthesis of <i>α</i>-Trifluoromethylated <i>α</i>-Amino Acids
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Stereoselective approaches to α-trifluoromethylated α-amino acids (α-Tfm AAs) have been developed. The stereoconfigurations of the resulting α-Tfm AA precursors were well controlled by using different solvents. The optically active (S)-2-amino-2-phenyl-1,1,1-trifluoropropanoic acid was synthesized by this method.
创建时间：
2016-05-05
