Crystal structure of mouse CARM1 in complex with inhibitor LH1236
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Crystal structure of mouse CARM1 in complex with inhibitor LH1236 Descriptor: (2~{R})-4-[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl-[[4-azanyl-1-(methoxymethyl)-2-oxidanylidene-pyrimidin-5-yl]methyl]amino]-2-azanyl-butanoic acid, 1,2-ETHANEDIOL, 1-METHOXY-2-(2-METHOXYETHOXY)ETHANE, ... Authors: Cura, V, Marechal, N, Troffer-Charlier, N, Halby, L, Arimondo, P, Bonnefond, L, Cavarelli, J. Deposit date: 2016-09-12 Release date: 2017-09-20 Last modified: 2025-12-10 Method: X-RAY DIFFRACTION (2.341 Å) Cite: Hijacking DNA methyltransferase transition state analogues to produce chemical scaffolds for PRMT inhibitors. Philos.Trans.R.Soc.Lond.B Biol.Sci., 373, 2018
创建时间：
2016-09-12
