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Expression data of B lymphocytes isolated from C57BL/6 Tilcara (Til) mouse mutant compared with wild-type C57BL/6 mouse [microarray]

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE137465
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Recent studies show that PKCs can have a nuclear function as epigenetic enzymes to directly regulate gene expression in the immune system. Using a PKCβ mutant mice model, C57BL/6 Tilcara (Til) mouse mutant, we examined the role of PKCβ as a histone kinase in regulating inducible gene expression in immune cells. We investigated if PKCβ is important for the expression of key inducible genes upon B cell activation. 4 biological samples.
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2022-09-17
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