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Ability of membTF mutants to support activation of FX and FIX, and clotting of plasma.

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aData are mean ± standard deviation of normalized rates of FX and FIX activation, and clotting activities, using membTF mutants in 5% PS/95% PC vesicles. Eight mutants selected for study are boldfaced. bNot determined. cKirchhofer et al. [3], using sTF with either SW-13 cell membranes or 500 µM 70% PS/30% PC liposomes. dRuf et al. [24], using detergent lysates of cells transfected to express membrane-anchored TF. eRehemtulla et al. [32], using detergent lysates of cells transfected to express membrane-anchored TF. fRoy et al. [30], using detergent lysates of cells transfected to express membrane-anchored TF, diluted in a buffer with 100% PC vesicles. gRuf et al. [31], using detergent lysates of cells transfected to express membrane-anchored TF.

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2014-02-06
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