Adjuvant comparison; CSP-specific CD4 T cell responses induced by RTS,S/AS01E and RTS,S/AS02D administered at 0,1- and 0,1,7-months (data pooled for both study sites) at peak (one month post last vaccination) and at study end (month 19).

N (%): Number of subjects per group and percentage responders (defined as a response ≥ geometric mean + 3 standard deviations (on the log 10 scale) of background stimulation).M (Q1–Q3): Results are expressed as the median (Q1 and Q3) number of CSP-specific CD4 T cells per 106 CD4 T cells.P-values for comparison of RTS,S/AS01E and RTS,S/AS02D were calculated using the mixed model procedure adjusted for multiple comparison using the Bonferroni method to correct for type I error.