Comparison of classification approaches.

The table shows the median classifier performance (AUC) of the classification problems considering different numbers of groups (2, 3 and 4) and models (SVM and RF). Performance of the standard SVM is compared to the elastic SCAD SVM (a). Performance of the RF per holdout sample using the miRNAs selected by the RF is compared to the RF per holdout sample using the miRNAs selected by the elastic SCAD SVM (b). Performance of the RF using the top 50% of the miRNAs most frequently selected by the RF across all runs is compared to the RF using the miRNAs selected by the median performing elastic SCAD SVM (c). For each comparison performance estimates based on miRNAs selected by the elastic SCAD SVM are enclosed in parentheses.