Pelletized growth in Cordyceps militaris is associated with coordinated cell wall remodeling and stress defense
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SARS-CoV-2 Nsp14 mediates the effects of viral infection on the host cell transcriptome
We performed a transcriptomic analysis of H293T cells expressing individual SARS-CoV2 proteins. Overexpression of Nsp14, a protein known to be involved in viral RNA replication, provoked a dramatic re
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Full-Length Transcriptome and Regulation Network in Response to Drought and Salt Stresses in Alfalfa (Medicago sativa L.)
Three alfalfa genotypes: Wilson (drought resistance), Saranac (drought-sensitive), PI467895 (salt resistance) were used for unraveling the alfalfa response to drought and salt stress through full-leng
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Characterization of Fetal Specific Transcriptional Programs in Thymic Epithelial Cells Identifies Myc as a Critical Determinant of Thymus Size [bulk RNA-Seq]
The thymus is the site of T cell development. Although much is known about the development and differentiation of the T lymphocyte compartment, less is known about the thymic epithelial cell (TEC) pop
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EWS::FLI cooperatively binds at GGAA microsatellites via DBD-a4 helix in TTC-466 [H3K27ac_CnT]
Multi-omics study of DBD-a4 helix of EWS::FLI to understand the underlying mechanism of transcriptional regulation in Ewing sarcoma cell line: TTC-466 In TTC-466 cells, we knock-down endogenous EWSR1:
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MCRS1 sensitizes pancreatic cancer to T cell immunity [cellline RNA]
Pancreatic cancer is one of the deadliest cancers in humans and is yet refractory to immunotherapy. Identifying factors that can sensitize pancreatic cancer to immune cells may thus hold the key to im
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