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Functional characterization of DNA methylation in the oligodendrocyte lineage [RNASeq_development]

ChEBI2016-04-14 更新2026-07-12 收录

胶质细胞表观遗传学

神经髓鞘发育调控

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-66029 数据链接链接失效反馈

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Functional characterization of DNA methylation in the oligodendrocyte lineage [RNASeq_development]

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创建时间：

2016-04-14

胶质细胞表观遗传学

基因敲除模型

Hdac1 and 2 are important regulators of developmental processes. In this study we created microglia specific compound Hdac1 and Hdac2 knock out mice. Pre-natal ablation of both Hdac1 and 2 from microg

NIAID Data Ecosystem50

Disease-associated astrocyte epigenetic memory promotes CNS pathology [For 3 times stimulation and Germ Free Mice]

胶质细胞表观遗传学

神经病理机制

Disease-associated astrocyte epigenetic memory promotes CNS pathology In this study we generated ATAC-Seq data from TNF-Alpha and PBS stimulated astrocytes from Germ Free Mice and Normal Mice. Normal

NIAID Data Ecosystem50

Microglia isolated from juvenile offspring of dams with allergic asthma exhibit methylation and transcriptional alterations to autism risk genes [WGBS]

母体免疫激活与自闭症

胶质细胞表观遗传学

Asthma is one of the most common chronic diseases among pregnant women, and symptoms often worsen during pregnancy. Dysregulation in immune responses during pregnancy, such as those that develop with

NIAID Data Ecosystem30

TET2 regulates the neuroinflammatory response in microglia

炎症调控

胶质细胞表观遗传学

Epigenetic mechanisms regulate distinct aspects of the inflammatory response in various immune cell types. Despite a central role for microglia in neuroinflammation and neurodegeneration little is kno

NIAID Data Ecosystem50

Injury-induced enhancer remodelling in spinal microglia - a novel mechanism for pain chronification? [ChIP-Seq]. Mus musculus

神经性疼痛

胶质细胞表观遗传学

Chronic pain is common and devastating. Yet, its precise molecular origins remain unclear. The condition induces well-characterised changes in neurons and microglia, but it is unknown why they persist

NIAID Data Ecosystem40

Functional characterization of DNA methylation in the oligodendrocyte lineage [RNASeq_development]

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