Microwave Assisted Tandem Heck–Sonogashira Reactions of N,N-Di-Boc-Protected 6‑Amino-5-iodo-2-methyl Pyrimidin-4-ol in An Efficient Approach to Functionalized Pyrido[2,3‑d]Pyrimidines
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资源简介：
A microwave assisted tandem Heck–Sonogashira cross-coupling reaction between 6-N,N-di-Boc-amino-5-iodo-2-methyl pyrimidin-4-ol and various aryl alkynyl substrates has been developed. This process generates novel 5-enynyl substituted pyrimidines, which can be transformed to novel functionalized pyrido[2,3-d]pyrimidines by way of a silver catalyzed cyclization reaction.
创建时间：
2016-02-17
