We observed a significantly better maximal inhibition for all cytokines with FF compared to MF. Furthermore, a significant inhibition was reached for all cytokines with FF, whereas MF failed to signif

NIAID Data Ecosystem20

Inhibition of Secretion of Interleukin-1α and Tumor Necrosis Factor Alpha by the Ketolide Antibiotic Telithromycin

免疫调节药物

细胞因子抑制

The antibiotic telithromycin was examined for its effect on secretion of interleukin-1α (IL-1α), IL-1β, IL-6, IL-10, and tumor necrosis factor alpha (TNF-α) by lipopolysaccharide (LPS)-stimulated mono

PubMed Central10

Chemical Genetics Screening Reveals KIAA1363 as a Cytokine-Lowering Target

疾病靶点发现

细胞因子抑制

Inflammation is a hallmark of many human diseases, including pain, arthritis, atherosclerosis, obesity and diabetes, cancer, and neurodegenerative diseases. Although there are several successfully mar

NIAID Data Ecosystem40

Suppressive effect of the anesthetic Propofol on the T cell function and T cell-dependent immune responses

麻醉药物免疫调节

T细胞功能调控

General anesthesia is thought to suppress the immune system and negatively affect postoperative infection and the long-term prognosis of cancer. However, the mechanism underlying immunosuppression ind

NIAID Data Ecosystem20

Regulation of cytokines: lidocaine vs. isoflurane (% inhibition)

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