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The DMC1-ssDNA complex preferentially targets to the nucleosome-free DNA region in human chromosomes. Homo sapiens

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NIAID Data Ecosystem2026-03-08 收录
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Chromatin fragments from HeLa cell extract by sonication were incubated with the DMC1-ssDNA complex or the RAD51-ssDNA complex. The chromatin fragments associated with the DMC1-ssDNA complex or the RAD51-ssDNA complex were pelleted using the magnetic beads conjugated at the edge of the ssDNA. The genomic DNA fragments associated to the DMC1-ssDNA complex or the RAD51-ssDNA complex were then analyzed by deep sequencing.

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2015-03-02
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