RAGE and Rap1a in Cardiac Hypertensive Remodeling
收藏NIAID Data Ecosystem2026-05-10 收录
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This study reveals that Rap1a knockout protects against AngII-induced cardiac hypertrophy, while RAGE knockout alters remodeling patterns. Despite genotype, AngII consistently drove structural changes, while diastolic function was genotype-dependent. These findings underscore the therapeutic potential of targeting Rap1a and RAGE signaling pathways to mitigate hypertensive cardiac remodeling.
创建时间：
2025-11-19
