Crystal structure of HCV NS3/NS4A protease complexed with des-bromine analogue of BI 201335
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Crystal structure of HCV NS3/NS4A protease complexed with des-bromine analogue of BI 201335 Descriptor: HCV non-structural protein 4A, HCV serine protease NS3, N-[(cyclopentyloxy)carbonyl]-3-methyl-L-valyl-(4R)-N-[(1R,2S)-1-carboxy-2-ethenylcyclopropyl]-4-[(7-methoxy-2-{2-[(2-methylpropanoyl)amino]-1,3-thiazol-4-yl}quinolin-4-yl)oxy]-L-prolinamide, ... Authors: Lemke, C.T. Deposit date: 2010-10-14 Release date: 2011-01-26 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Combined X-ray, NMR, and kinetic analyses reveal uncommon binding characteristics of the hepatitis C virus NS3-NS4A protease inhibitor BI 201335. J.Biol.Chem., 286, 2011
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2010-10-14



